Nanomaterial and Nanostructure Characterization

We have expertise in using numerous analytical techniques to characterize carbon nanoparticles including:

  • Thermogravimetric Analysis (TGA)
  • Raman spectroscopy
  • Inductively-coupled Mass Spectrometry (ICP-MS)
  • Fourier Transform Infrared Spectroscopy (FTIR)
  • X-ray Photoelectron Spectroscopy (XPS)
  • Scanning Electron Microscopy (SEM)
  • Transmission Electron Microscopy (TEM)
  • Ultraviolet-Visible-Near Infrared Spectroscopy (UV-VIS-NIR)
  • Near Infrared Photoluminescence (NIR-PL)
  • Dynamic Light Scattering (DLS)
  • Atomic Force Microscopy (AFM)
  • Confocal Raman Spectroscopic Imaging

Please contact us if you are interested in learning more about how we use these techniques to provide a thorough assessment of bare and conjugated carbon nanoparticle quality.

Nanoparticle Cytotoxicity Testing

We are establishing a suite of assays that will enable in-depth analysis of the effect of carbon nanoparticles on the proliferation of mammalian cells in culture.

Assays under development include:

  • Crystal violet assay
  • Coulter counter
  • Live/dead cell assays
  • MTT assay
  • Cell colony plating efficiency assays
  • Customized assays

In Vitro Assessment

Using a proprietary set of protocols and tools, we can thoroughly characterize the biological activity of your nanostructures by providing any of the following analyses:

  • validate nanoparticle conjugation
  • evaluate nanostructure cytotoxicity
  • assess cell targeting capability of nanoparticles and their conjugates
  • determine subcellular destination of nanoparticles and their conjugates

Nanoparticle Conjugation

As part of our nanoparticle conjugation services, we can provide biologically-targeted conjugations of the following carbon nanoparticles:

  • carbon nanotubes (CNTs)
  • graphene oxide
  • nanodiamond (coming soon)

Biological targeting agents that we can conjugate to your carbon nanomaterials include:

  • Antibodies
  • Peptides
  • Proteins
  • SiRNA

For other carbon-based nanomaterials or other targeting agents, please give us a call or fill out our Contact Us form.